AKIPRESS.COM - Tens of thousands of black-clad protesters angry at the presumed slaughter of 43 students marched in Mexico City, chanting for President Enrique Pena Nieto's resignation, reports AFP.

In the latest day of nationwide demonstrations, protesters waved blackened Mexican flag, shouting "Urgent! Urgent for the president to resign!" and "He will fall, he will fall, Pena Nieto will fall!"

Parents of the 43 male college students, who reject claims their sons are dead, led the march to the historic Zocalo square, in front of the National Palace.

It was the latest protest over the government's handling of a crime that has infuriated Mexicans fed up with corruption, impunity and a drug war that has left more than 100,000 people dead or missing since 2006.

The case has turned into the biggest challenge of Pena Nieto's nearly two-year-old presidency, on top of another scandal over a mansion his wife bought from a government contractor.

Prosecutors say a drug gang confessed to slaying the students and burning their bodies after receiving them from corrupt police in the southern state of Guerrero in September.

"Mexico is used to tragedy, robberies and corruption, and we need to begin to exercise our rights as citizens to get the government working," said Lili Correa, 46, wearing black.

The demonstration coincided with the anniversary of the start of the 1910 Mexican revolution, prompting the government to cancel the annual parade.

Before the march, masked protesters threw firebombs and used bazooka-like tubes to launch firecrackers at riot police, who hit back with tear gas to disperse the group on a street near the airport. Around 15 people were detained.

Hundreds of protesters blocked the main road to the airport for an hour, while police vehicles picked up passengers walking with their suitcases along the road.

Thousands protested in several other cities, including Chilpancingo, the capital of Guerrero, the violence-plagued southern state where the students vanished nearly two months ago.

Thousands more marched in Bolivia and some 200 took to the streets in El Salvador.

Mexico and Real Madrid football star Javier "Chicharito" Hernandez tweeted a picture of himself wearing a black hoodie and the hashtag #WeAreAllAyotzinapa, referring to the young men's Ayotzinapa teacher-training college.

"This is a nationwide problem. Nothing like this happened before and Pena Nieto doesn't care, he's useless," said Luis Angel Garcia, a 19-year-old Ayotzinapa student.